10.1155/2019/5080843 76 SuY.ZhaoB.ZhouL.ZhangZ.ShenY.LvH.et al (2020)
Treatment Investigation of cause and elimination if possible Prognosis Excellent Physiologic Pigmentation Etiology Normal melanocyte activity Clinical Presentation Seen in all ages Symmetric distribution over many sites, gingiva most commonly Surface architecture, texture unchanged Diagnosis History Distribution Differential Diagnosis Mucosal melanotic macule Smoking-associated melanosis Superficial malignant melanoma Treatment None Prognosis Excellent Smokers Melanosis Etiology Melanin pigmentation of oral mucosa in heavy smokers May occur in up to 1 of 5 smokers, especially females taking birth control pills or hormone replacement Melanocytes stimulated by a component in tobacco smoke Clinical Presentation Brownish discoloration of alveolar and attached labial gingiva, buccal mucosa Pigmentation is diffuse and uniformly distributed
Dream Team: 325mg of highly absorbable magnesium bisglycinate clinically dosed for optimal sleep and gentle on digestion.* L-Theanine shown to promote relaxation in 45 minutes** **Based on a randomized controlled trial in 35 adults who received 50 mg of L-theanine or placebo
However, the necessity of GPxs for eukaryotic cells is justified considering that GPx can neutralize not only inorganic (hydrogen peroxide) but also organic peroxides (including lipid hydroperoxide)
The exact process occurs with each of the agentsFAD, NADPH, and FMNbut not with cyanocobalamin, which does not interact with these biological agents at all
