do you lose weight in first week of semaglutide What Should I Expect During the GLP-1 Semaglutide, also known as Ozempic,

Once you stop taking the GLP-1 drugs, the lost weight rapidly returns, and the metabolic benefits of the initial weight loss quickly erode (2)

Joshua Stewart, MD, a reproductive endocrinologist at Weill Cornell Medicine

J Appl Physiol (1985) 109(3):721727

The 5 main classes of antidiabetic drugs are: Metformin (Biguanides) first-line treatment Sulfonylureas (Glimepiride, Gliclazide) stimulate insulin release SGLT2 Inhibitors (Jardiance, Forxiga) flush sugar through urine GLP-1 Agonists (Ozempic, Trulicity) gut hormone mimics DPP-4 Inhibitors (Januvia, Galvus) protect natural gut hormones Your doctor selects the right combination based on your HbA1c, weight, kidney function and budget

IGF-1 signalling studied for downstream growth-factor effects