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The Sulfur Factor Glutathione is a sulfur-containing molecule

Compared with Control cells, p53 KO cells exhibited far fewer nutlin-3induced changes in gene expression, consistent with most changes observed in Control cells being p53-dependent (Fig 3A)

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A strong peak at 1730 cm reveals the presence of ester functional groups due to the C = O stretching vibration

The duration effect suggests GHK-Cu induces cumulative structural changes in dermal architecture where longer treatment allows more complete remodeling supporting ongoing enhanced function without continuous peptide presence