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Heatmap analysis showed partial separation between improved and non-improved patients across domains alongside substantial inter-individual variability ( Figure 2B )

Physiol Rev 81:299343 [DOI] [PubMed] [Google Scholar] Wolf R, Koch T, Schulz S, Klutzny M, Schrder H, Raulf E, Bhling F, Hllt V

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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action As a copper chelator, GHK-Cu modulates over 4,000 human genes, upregulating those involved in tissue remodeling (e.g., collagen I, III) and downregulating pro-inflammatory pathways like NF-B

It will also present possible methods for the use of therapeutic GHK in the treatment of nerve diseases