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They can support healthy B12 levels, but they are not as effective as injections

(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)

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Antidiabetogenic Effect of Glucagon-like Peptide-1 (736)amide in normal subjects and patients with diabetes mellitus

the evidence base is still developing, so we frame this as a mechanism under investigation rather than a settled outcome