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As for the PV2 nanobody, mutants S26pAcF, S71pAcF, and Q82pAcF showed Tm values of 52.2 C, 52.9 C, and 53.1 C, higher than 47.9 C of wild type

Patients should be advised to: Check fasting glucose regularly, especially if taking insulin or sulfonylureas Monitor pre- and post-meal glucose periodically to assess postprandial control Record symptoms of hypoglycaemia (blood glucose 15 mmol/L) [5] Report concerning patterns to their diabetes care team promptly Medication adjustments are frequently necessary

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