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Insulin resistance and PCOS: Patients with severe insulin resistance or polycystic ovary syndrome (PCOS) may have a more complex metabolic profile that requires additional intervention beyond GLP-1 therapy alone

Commentary: The expanding benefits of GLP-1 medicines

Biguanides (metformin): Medications used to treat type 2 diabetes, metabolic syndrome, nonalcoholic fatty liver disease, and polycystic ovary syndrome can lead to decreased vitamin B12 absorption (5)

(7) Kong YX, Li ZS, Liu YB, Pan B, Fu X, Xiao R, Yan L

How Zepbound Works: The Science of Dual Agonism Zepbounds efficacy stems from its unique mechanism of action as a dual agonist