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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimers disease

In the words of Gustavo Bounous, MD, retired professor of surgery at McGill University in Montreal, Its the [bodys] most important antioxidant because its within the cell. Although its absolutely essential to maintaining a healthy immune system, it is not technically an essential nutrient because the body can create it from the amino acids L-cysteine, L-glutamic acid (a component of glutamine) and glycine

Schook CC, Mulliken JB, Fishman SJ, Alomari AI, Grant FD, Greene AK

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In other words, G6PD is an X-Linked recessive condition which means that males are more susceptible to complications driven by G6PD deficiency than are the females