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The 2024 NICE Guideline NG239 from the United Kingdoms National Institute for Health and Care Excellence similarly distinguishes between patients who can be managed with oral therapy and those who require intramuscular treatment

The peptide shows potential neuroprotective properties

Ilic S, Brcic I, Mester M, et al

GHK and GHK-derived targeting peptides facilitated scratch repair by accelerating collagen synthesis and glycosaminoglycan secretion (Figure 6A)

The SUSTAIN and STEP trial data consistently showed cardiometabolic improvements in lipid profiles alongside weight loss, which is part of why semaglutide received approval for cardiovascular risk reduction in certain populations