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Torsins: not your typical AAA + ATPases

NRF2, Nuclear factor erythroid 2-related factor 2 Background NADPH, the reduced form of nicotinamide adenine dinucleotide phosphate (NADP + ), is an essential co-factor for enzymes that catalyze a wide variety of oxidative and antioxidative processes [1]

An immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge (white bars), pyloric sphincter seems to be less affected

(Its actually ideal for preventing oxidation!)

Theres some promise when it comes to using berberine as a supplement, but its important to talk to your healthcare provider beforehand