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Bramham CR, Southard T, Ahlers ST, Sarvey JM (1998) Acute cold stress leading to elevated corticosterone neither enhances synaptic efficacy nor impairs LTP in the dentate gyrus of freely moving rats

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In clinical trials such as the STEP programme for semaglutide 2.4mg (Wegovy), fatigue was reported more frequently in patients receiving the active treatment compared to placebo

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29 However, in their 2021 guidelines, the ACG recommends against antispasmodics available in the United States, namely dicyclomine (Bentyl), hyoscyamine (Levsin, among others), and hyoscine (Scopolamine), due to lack of evidence supporting their efficacy