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If the GLP-1/GIP/glucagon receptor class shows disease-modifying behaviour in OA rather than just mechanical pain relief from weight loss, it expands the scientific rationale for the compound and reinforces the argument that the triple-agonist mechanism is doing more than suppressing appetite

TRIUMPH-4: Metabolic findings beyond weight TRIUMPH-4 also produced two metabolic findings that are relevant beyond weight loss itself

Crucially, this is the same route used in the clinical research behind these ingredients (7)

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It tends to peak within 24 to 72 hours after injection and fade over the next few days