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A 68-week randomised controlled trial of semaglutide in adults with overweight or obesity (without diabetes) found that while approximately 39% of the total weight lost was lean mass, this was within an acceptable clinical range and mostly proportional to the degree of total weight loss [4]

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GLP-1 medications work by High levels of the GLP-1 hormone can also reduce your appetite and increase feelings of fullness by slowing the rate at which your stomach empties, which can aid with weight management

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