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True metabolic healing that lasts requires deeper work that targets: Insulin resistance at the cellular level Chronic inflammation that affects ovulation and egg quality Nutrient deficiencies like zinc, magnesium, vitamin D, and choline Hormone signaling issues , including leptin resistance, estrogen dominance, or HPA axis dysregulation Without resolving these, even if your weight drops, your body may still perceive pregnancy as unsafe

In other words, barely 1 in 7 patients remains on GLP-1 therapy after two years , despite obesity being a chronic condition requiring long-term treatment

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Lancet Diabetes Endocrinol 6, 275-286