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Weight loss injections, particularly glucagon-like peptide-1 (GLP-1) receptor agonists, can significantly impact gastrointestinal function

Clinicians should also screen for eating disorders or mood changes, since the psychosocial effects (positive or negative) of pharmacologic weight loss in youth are not yet fully understood (43)

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Food, beverages other than plain water, and other medications significantly reduce semaglutide absorption from the gastrointestinal tract

Body-composition shifts tend to emerge later, and connective-tissue benefits tendon resilience, joint comfort, recovery typically take several months to become apparent