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10.1016/j.nbd.2021.105510 Neurobiol

Wunsch K, Fiedler J, Bachert P, Woll A

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Most GLP-1 side effects (nausea, constipation) are mild and transient, but the clinical team helps distinguish normal adjustment from concerning reactions

Collectively, these data suggest that enrichment of Escherichia-Shigella is not only a compositional hallmark of RE-associated dysbiosis but also a functionally relevant pathobiont shift that couples barrier collapse with IL-6-JAK/STAT3-driven and TLR4-NF-B-driven increased inflammatory responses, thereby sustaining a feedforward injury loop 120