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However, after initial sensitivity, many patients develop resistance to treatment 42,43

For example, in pea plants susceptible to Plum pox virus (PPV), systemic PPV infection produced chlorotic and necrotic lesions, a pronounced oxidative stress indicated by increased protein oxidation, lipid peroxidation, elevated H 2 O 2 levels and electrolyte leakage in infected leaves (Daz-Vivancos et al., 2008)

Multiple studies have provided evidence indicating the protective role of ghrelin in the development of esophageal disorders, gastric disorders, GI functional disorders, and CC

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