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For example, compared to individuals without these inflammatory conditions, patients with psoriatic arthritis have a 90% higher risk of hypertension [203], those with rheumatoid arthritis have a 50% higher risk [204], and individuals with periodontitis have a 22% increased risk of hypertension [205]

Paraptosis can be induced by various triggers, such as activating the insulin-like growth factor 1 receptor (IGF1R), proteasomal inhibition leading to ER stress, ROS generation, and calcium influx into mitochondria

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