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An Australian study estimated that nearly one in five future TC cases could be attributed to current overweight or obesity [195]

In patients with osteoarthritic symptoms, fulranumab demonstrated greater efficacy than an opiate, although, in low back pain, no benefit over a placebo was seen [32]

The clinical case for long-term obesity pharmacotherapy has been strengthened by SELECT trial cardiovascular outcome data, growing insurance coverage mandates, and the demonstrated durability of weight loss maintenance in patients who remain on GLP-1 therapy

doi:10.1016/j.redox.2020.101585 Ahmed M, Cerda I, Maloof M