Rocha-Ferreira E, Poupon L, Zelco A, Leverin AL, Nair S, Jonsdotter A, et al
Physiologic action of glucagon on liver glucose metabolism
Up-regulation of HO-1 levels in the cell is a hallmark of oxidative stress, with downstream effects especially in the pro-oxidative state [48, 49]
"Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes"
For a long time, the manifestation of depressive symptoms has been also associated with the deficits in neurotrophic factor action in the brain [51], especially highlighting the role of diminished brain-derived neurotrophic factor (BDNF) signaling as important for the pathogenesis of this mental disorder [52]