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Gastrointestinal symptoms are the predominant side effects and include: Nausea very common (may affect more than 1 in 10 people) Diarrhoea very common Vomiting common (may affect up to 1 in 10 people) Constipation common Abdominal pain or discomfort common These gastrointestinal effects are usually mild to moderate in severity and tend to diminish over time as the body adjusts to the medication

Management strategies depend on severity

By helping to reduce blood pressure and lowering LDL (bad) cholesterol, these drugs contribute to a healthier heart profile

In practice, providers who work with patients starting a GLP-1 medication often observe that appetite changes tend to become noticeable before meaningful shifts on the scale, sometimes within the first two to four weeks of consistent use

Stop taking Saxenda and contact your doctor immediately if you develop persistent severe abdominal pain, which may radiate to your back, with or without vomiting