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There are receptors for these hormones distributed across many tissues and their effects are thus pleiotropic

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The consumption of fewer calories, in addition to sufficient protein intake, has proved to be another effective approach to treating PCOS symptoms

"Originally that was thought to be mostly skeletal, we're starting to see some evidence that's smooth, and even cardiac tissue that's being lost as well." This shift is pushing researchers to look beyond the simple calories-in-calories-out equation