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The novel isoform is derived from a repeat sequence (ATGAGGT) in both exon 4 and exon 6 following a mechanism for the regulation of pre-mRNA alternative splicing (Figures 4B,C) (Figure 4D and Supplementary Figure S6)

Same active ingredient, different FDA indications, different coverage logic

reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)

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Dzierzewicz, Effect of GLY-HIS-LYS and its copper complex on TGF- secretion in normal human dermal fibroblasts, Acta Pol