Treating the metabolic conditions becomes part of treating the osteoarthritis. Research has shown that patients with type 2 diabetes are more likely to have severe osteoarthritis as well as a higher likelihood of needing revision surgeries after knee replacements
GLP-1, a hormone produced by L cells in the jejunum, ileum, and colon, is released in response to nutrients (DAlessio, 2016)
ISF induced gastric and intestinal distension, which increased circulating GLP-1 levels and activated a subset of vagal sensory neurons (Fig
The biosimilars business continued to perform strongly, supported by major launches: Pyzchiva (ustekinumab) was launched in the US in February 2025, offering new treatment options for around 12 million patients with chronic inflammatory diseases such as psoriasis and psoriatic arthritis
Psyllium husk, or ispaghula husk, is a fiber supplement made by grinding the outer layer of psyllium seeds from Plantago ovata , a medicinal plant grown in India