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The choice depends on individual risk tolerance, budget constraints, and comfort level with unvalidated treatments

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Then, the heart was dissociated by pipetting, and digestion was terminated with stop buffer

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Notably, 5-22% of tumors that develop resistance to EGFR tyrosine kinase inhibitors (TKIs) exhibit c-MET amplification, demonstrating the tumors capacity to exploit multiple signaling mechanisms to bypass therapeutic inhibition [8]

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