Understanding the link between antimicrobial properties of dietary olive phenolics and bacterial ATP synthase
While lipophilicity, dipole moment, and size are factors that influence the ability of a compound to enter the hydrophobic core of a cell membrane, the lipid bilayer environment is too chemically complex, fluid, and heterogeneous for these indicators alone to provide accurate estimates of transport kinetics
(2022) Cancer Res 82, 3209-3222
International Journal of Pharmaceutics , 249(1-2), 101108.) Polymeric nanoparticles are with pharmaceutical advantages: 1) Comparing to other colloidal carriers like liposomes, they are more stable in the GI tract and can prevent encapsulated drugs damaging from the GI environment
Researchers already experienced with GLP-1 compounds who understand titration, injection technique, and side effect management are better equipped to handle the complexity of a dual-peptide protocol