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Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury

EC 2.5.1.18) are part of a superfamily of enzymes that play a crucial role in cellular detoxification

Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis

However, deficiency is rare in the U.S., where people are more likely to be at risk for excess vitamin A