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In a mouse model of pancreatic cancer liver metastasis, the use of IGF-IR inhibitor IGF-Trap reshaped the local immunosuppressive microenvironment of liver tumors, reduced the recruitment of bone marrow-derived suppressor cells, reversed innate immune cell polarization and inhibited metastatic expansion

& Niehrs, C

Hamamah, S., Aghazarian, A., Nazaryan, A., Hajnal, A

So again, it doesnt make sense, because remember, the premise of this law was that were going to look at drugs that have no generic competition, that they dont have any biosimilar competition, and were going to basically start price setting them

This analysis is depicted in Fig