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Sen O, et al

Barrier integrity is maintained through multiple mechanisms, including mucus layer secretion, antimicrobial peptide production, and immunoglobulin A (IgA) secretion (Odenwald and Turner, 2017)

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Other pharmacotherapies not based on entero-pancreatic hormones Several therapies that are not based on entero-pancreatic hormones are currently under evaluation for obesity and they represent further therapeutic options, considering their distinct mechanism of WL to the entero-pancreatic hormone therapies

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