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In this context, we summarize the mechanism of conversion of endogenous molecules to DAMPs, their release pathways, classification systems, recognition modes, and their pathological roles in various diseases, and explain in detail current therapeutic strategies for DAMPs/PRRs, including cell death pathway modulation, monoclonal antibody interventions, signaling pathway inhibition, and gene silencing technologies, and discuss the challenges of these therapeutic strategies

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Ipamorelin is a selective growth hormone secretagogue targeting the ghrelin receptor (GHS-R1a)

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