GSLs, the precursors of ITCs, constitute in addition to their role in defence responses a storage for reduced sulfur as well as a good example on how the partitioning of this macronutrient is controlled between primary and secondary metabolism 82
GHK-Cu is a naturally occurring copper-binding tripeptide studied in laboratory environments for its interaction with extracellular matrix signaling pathways, copper transport activity, and peptide-mediated gene expression models
Moreover, upregulation of the Wnt/-catenin signaling pathway has been implicated in cabazitaxel resistance by enhancing cell survival and promoting an EMT phenotype, which is associated with increased metastatic potential and drug resistance (57)
Additionally, toll-like receptor 4 (TLR4) can induce necroptosis via interaction between the toll receptor-associated activator of interferon (TRIF) and the necrosome (Solon et al., 2024)
L-carnitine facilitates the mitochondrial eta-oxidation process and energy production by mediating the transport of long-chain fatty acids into the mitochondrial matrix (Ribas et al