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In patients with type 2 diabetes, semaglutide prescription was associated with 0.13% risk of first-time suicidal ideations and 10% for recurrent ideation, compared to 0.36% and 18%, respectively, for other diabetes medications

The mean age was 52 years old, 70.5% were women and the mean baseline weight was 242.5 pounds

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Muscarella et al., 2011b), prostate (Zhang et al., 2010), malignant glioma (Muscarella et al., 2011a), and colorectal cancers ( KEAP1 gene expression results in NRF2 accumulation, conferring a survival and growth advantage to cancer cells