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The University of North Carolina at Chapel Hill launched one of the first randomized controlled trials examining semaglutide specifically for alcohol use disorder

First, the sample size was relatively small, which may limit the generalizability of the results

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This means it not only affects the GLP-1 pathway but also stimulates GIP (glucose-dependent insulinotropic polypeptide) receptors, For this reason, tirzepatide offers more levers for weight loss