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However, 5 years of follow-up indicated that within that period, after vagotomy, there is a reduced risk of PD, and very similar results were obtained in the 10-year follow-up

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PMID 28100881

This is achieved by promoting the hosts protective indoleamine-2,3-dioxygenase 1/kynurenine pathway while restricting the microflora-activated indole/aryl hydrocarbon receptor pathway

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