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What are the main differences between these two medications

The patients most likely to show a divergent psychiatric response to GLP-1 therapy those with comorbid SUD, prior mood episode history, or active anhedonia at baseline are exactly the patients who get excluded for psychiatric instability. The result is a Phase 3 dataset that proves efficacy in a population cleaner than anyone sitting in an actual psychiatric clinic

The authors of this report also note that a vast number of drug overdose deaths involve more than one drug

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Mounjaro is for type 2 diabetes management, while Zepbound aids chronic weight management in adults with obesity, or those who are overweight with weight-related health conditions like high blood pressure or high cholesterol