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[1] Dehydration from gastrointestinal side effects can increase the risk of acute kidney injury

A 57-year-old woman taking dulaglutide injections every week for over a year began experiencing nausea, vomiting and bloating associated with delayed gastric emptying within three months of starting the prescription medication

Nutrients, 13 (10), 3483

176 In 1906, after the discovery of secretin, it was first tested if the gut aided the pancreas with disposing of nutrients via stimulation of pancreatic internal secretion by Moore and colleagues, who orally administered porcine small intestinal extract to treat diabetic patients

The question becomes: do you need to stay at the maximum dose to maintain results, or can you step down