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Anderson, Methods in Enzymo l., 1985 , 113 , 548
The mean fluorescence intensity (MFI) of rhodamine 123ES is indicated in the table
E3 ligases in metabolic diseases Insulin receptors and insulin receptor substrates (IRS-1 and IRS-2) are crucial for insulin signaling, and E3 ligases such as MG53, c-Cbl, and Nedd4 can directly degrade these substrates, disrupting signaling and promoting insulin resistance
The Growing Epidemic The World Health Organization (WHO) defines overweight for Asians as a Body Mass Index (BMI) of 23 kg/m or higher and obesity as 27.5 kg/m or higherthresholds lower than global standards due to the higher body fat percentage in Asians at lower BMIs
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