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This reduces their therapeutic effectiveness since they do not remain in the body long enough to perform their intended function

J Biol Chem 272:2308623093

10.1073/pnas.1112495109 18 Cervantes-MadridD.RomeroY.Dueas-GonzlezA

Cerebral energy metabolism and intracellular pH during severe hypoxia and recovery: a study using 1H, 31P and 1H[13C] NMR spectroscopy in the guinea pig cerebral cortex in vitro