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All 122,124,125,126,127,128 but one 123 study showed a benefit on metabolic parameters

Clinical recommendations based upon the patients renal function include [see Dosage and Administration (2.1, 2.4) and Clinical Pharmacology (12.3)]: Before initiating XIGDUO XR, obtain an estimated glomerular filtration rate (eGFR)

Ghrelin is an orexigenic peptide hormone secreted from stomach in response to fasting situations and stimulates the ghrelin receptor in the brain to initiate appetite 1,2,3,4

Some users may experience mild digestive discomfort, such as nausea or stomach upset, particularly when taken in high doses

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