When applied topically, they significantly strengthen and repair damaged skin barrier function to prevent moisture loss, reduce the chance of external irritants from harming the skin, and enhance the skin's defense capabilities, thereby improving symptoms like sensitivity, redness, and inflammation
Necrotic cell death increases the release of macrophage migration inhibitory factor by monocytes/macrophages
It has several important roles: Regulating blood glucose: GLP-1 increases insulin secretion and reduces glucagon levels, keeping blood sugar steady
She has a background as a nurse and I have no concerns going into procedures with her - I know her procedure room is clean and safe and I will be well-cared for
Implications for practice Following more than 6 months where initiation of GLP-1 RAs was not permitted in the UK, clinicians will have been pleased to read the National Drug Safety Alert published earlier this month, which confirms that there are now sufficient supplies of daily oral semaglutide (Rybelsus) available in the UK to allow new initiations as well as supplying those already on treatment
