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Diarrhea or constipation : Gastrointestinal effects are central to GLP-1 mechanisms

The commonly recommended timing, morning on an empty stomach 30-60 minutes before eating, maximizes fat oxidation effects but may increase nausea in sensitive individuals

A 2021 Nature Communications study then showed that MOTS-c is induced by exercise and that treating mice, including animals started late in life, boosted running capacity and physical performance across young, middle-aged, and old groups [3]

Tell your doctor immediately if you have any side effects

For milder cases, you might see subtle boosts in energy, brain fog reduction, and mood lifts within the first week or two