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Mast cell activation syndrome, or MCAS, is an immunological condition where the mast cells in the body release excessive amounts of chemical mediators such as histamine, leading to symptoms such as hives, flushing, rashes, swelling, low blood pressure, dizziness, brain fog, breathing difficulties, and even anaphylaxis

Conditions such as diabetes, obesity, or pre-existing spinal stenosis can extend recovery and make symptoms of sciatica harder to alleviate symptoms through conservative means alone

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