B12/MIC is generally well-tolerated and can be safely combined with other treatments like Metformin, NAD+, LDN, and longevity supplements
The right choice depends on your goals, health history, symptoms, medications, allergies, pregnancy or breastfeeding status, and whether a B12 shot, IV therapy, wellness injection, or medical consultation is the better next step
High NNMT expression is closely associated with glucose dysregulation: excessive NNMT activation disrupts nicotinamide metabolism, lowers NAD+ levels, impairs insulin signaling, reduces cellular glucose uptake and utilization, and promotes hyperglycemia and insulin resistance
This usually occurs in individuals with underlying digestive conditions, those who have trouble absorbing all nutrients through digestion, or those with pernicious anemia, which specifically prevents B12 absorption
Depending on your body and the severity of your deficiency, B12 injections can start to work in a matter of hours to a few days