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Retatrutide is not yet approved by any regulatory agency, meaning it is only available through research chemical suppliers

TABLE 1 Therapeutic actions of GLP-1 receptor agonists in liver disease: summary of experimental and clinical findings

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Hydrate aggressively GLP-1 medications reduce thirst along with hunger

Nausea is the most reported complaint in trials: It shows up most in the first few weeks as the dose increases and tends to settle meaningfully once a stable therapeutic dose is maintained, which is why the pace of escalation matters so much in how well patients tolerate it