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Sterile water does not contain preservatives, so it cannot prevent bacterial growth in a multi-dose vial

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The Pricing Spiral The dynamics of generic drug pricing after full market opening follow a predictable spiral: prices fall rapidly as competitors enter, margins compress until manufacturers with insufficient scale exit the market, and the remaining manufacturers stabilize at a price level that covers their marginal cost of production plus a minimal margin

Keim NL, Stern JS, Havel PJ

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