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Research progress on the mechanism of leucine regulation of protein synthesis in aging skeletal muscle through LAT1

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The side effects are real annoying at best and debilitating at worst and can include nausea, diarrhea, cramps and abdominal pain, constipation, vomiting, gastroesophageal reflux, gastroenteritis, pancreatitis, gastroparesis, intestinal obstruction, gall bladder disease, headaches and potential risk for certain types of thyroid and endocrine cancers, among other adverse effects

Despite its promise, several gaps need to be addressed prior to clinical translation

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