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B., Szabo, C

Some patients mistake early dehydration for medication side effects and reduce their GLP-1 dose unnecessarily, when simple fluid intake adjustment resolves the symptom

Randomised controlled trials involving GLP-1RA have not detected suicidality signals, but these studies were underpowered to detect rare events such as SIS, and they selectively exclude individuals with psychiatric comorbidity [23,24,25,26], which are prevalent in daily practice

Regulatory agencies have examined the potential for GLP-1 agonists to cause adverse psychiatric effects, including suicidal ideation

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