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The early success of these drugs in combating what was considered to be an intractable public health concern has begun to reshape how society is framing obesity as a health issue, leading to ripple effects that are affecting how food is sold and consumed, insurance and workplace wellness policies, and importantly, public attitudes surrounding the veracity of framing obesity as a medical issue that can and should be treated

For many patients who experience fatigue when starting GLP-1 therapy, symptoms often improve as the body adapts to the medication

Neither peptide has shown significant sedative, dependence-forming, or withdrawal-related properties in published studies

However, many users report that the time of day affects their side effect experience

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