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the process can obviously also be performed by initiating crystallisation by seeding the supersaturated solution with alpha crystals

A careful skeptic would say: the in-clinic procedure has solid evidence, the at-home extension is biologically plausible and consistent with the procedure, but the dataset is younger than the recommendation implies

Much of the research is preclinical, so we'll always frame expectations honestly

It can be highly activated by various stress stimuli, where it is required for the re-folding of damaged and unfolded proteins generated under stress 43

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