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Results On a patient level, Semaglutide 2.4 mg in addition to D&E compared to D&E alone, improved QALYs by 0.098 and yielded higher costs by 1,325 EUR over a 40-year time horizon, with an ICER of 13,459 EUR per QALY gained and 100% probability of cost-effectiveness at the given WTP

The choice of antihyperglycaemic treatment is usually based on comorbidities, baseline cardiovascular risk, side effects, cost and clinical assumptions, but rarely on measurements of pathophysiological features driving the deteriorating metabolic state that ultimately leads to complications 2

Never freeze reconstituted solution as this destroys peptide structure

Molecular Metabolism, 64, 101550

European Journal of Endocrinology, 1998;139(5):552-561